Unexpected Septal and Truncal Valve Endocarditis After Transcatheter Pulmonary Valve Replacement

Despite early clinical success of transcatheter pulmonic valve replacement, there is concern for an increased risk of endocarditis requiring complex surgery to repair. We present a case of endocarditis of a Melody (Medtronic, Minneapolis, MN) valve in a 33-year-old male patient with prior neonatal repair of persistent truncus arteriosus and 2 subsequent right ventricular outflow tract to pulmonary artery conduit replacements. The infection had extended from the Melody valve through the prior ventricular septal defect patch to the truncal valve and highlights the risk of endocarditis, particularly with the Melody transcatheter valve.