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Guide for paediatric radiotherapy procedures.

A Laprie1, V Bernier2, L Padovani3

  • 1Département d'oncologie radiothérapie, Institut universitaire du cancer de Toulouse-Oncopole (IUCT-oncopole), université Paul-Sabatier Toulouse III, 1, avenue Irène-Joliot-Curie, 31059 Toulouse cedex 9, France.

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique
|December 31, 2021
PubMed
Summary
This summary is machine-generated.

Paediatric radiotherapy is crucial for treating childhood cancers, with 800 irradiations annually in France. Updated guidelines address complex cases and long-term toxicity concerns for improved patient outcomes.

Keywords:
Brain tumourCancers de l’enfantEwing's sarcomaGuidelinesNeuroblastomaNeuroblastomePaediatric cancerProtontherapyRadiation therapyRadiothérapieRecommandationsRotonthérapieSarcome d’EwingSociété française de radiothérapie oncologiqueTumeurs cérébrales

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Area of Science:

  • Paediatric Radiation Oncology
  • Childhood Cancer Treatment
  • Radiation Therapy Techniques

Background:

  • Radiotherapy is a key treatment for approximately one-third of childhood cancers.
  • In France, 800 paediatric irradiations are performed annually across 15 specialized centers.
  • Common childhood cancers treated with radiotherapy include brain tumors, neuroblastomas, and sarcomas.

Purpose of the Study:

  • To present updated recommendations for paediatric radiation oncology in France.
  • To outline indications, technical methods, and organizational aspects of paediatric radiotherapy.
  • To address the complexities of treatment preparation and long-term toxicity in childhood cancer patients.

Main Methods:

  • Review of treatment guidelines from the French Society for Childhood Cancers (SFCE) and prospective protocols.
  • Discussion of complex cases during bimonthly paediatric radiotherapy technical web-conferences.
  • Inclusion of all available irradiation techniques: 3D conformal, intensity-modulated, stereotactic, brachytherapy, and proton therapy.

Main Results:

  • Overall survival for paediatric cancers is 80%, highlighting the importance of managing long-term toxicity.
  • Treatment preparation is complex due to the need to balance efficacy and toxicity.
  • A comprehensive range of radiotherapy techniques is utilized.

Conclusions:

  • Updated recommendations are essential for optimizing paediatric radiation oncology practices.
  • Standardized guidelines and collaborative discussions improve the management of complex paediatric cancer cases.
  • Focusing on long-term toxicity is critical for improving the quality of life for childhood cancer survivors.