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Survival After Minimally Invasive Surgery in Older Women With Endometrial Carcinoma
Joel Cardenas-Goicoechea1, Y U Wang2, Ji-Hyun Lee2,3
1Department of Gynecology. Division Gynecologic Oncology, Cleveland Clinic Florida, Weston, FL, U.S.A. joelcardenas@yahoo.com cardenj3@ccf.org.
Background/Aim:
To analyze the impact of minimally invasive surgery for endometrial cancer on overall survival among age >65.
Patients And Methods:
We examined women who underwent hysterectomy from 2010 to 2015 from the U.S. National Cancer Data Base (NCDB). We evaluated the impact of surgical approach on survival.
Results:
Of 243,601 endometrial cancer cases, 42,458 met the inclusion criteria. Laparoscopic approach was associated with improved survival by 14% (HR=0.86; 95%CI=0.80-0.92; p<0.001) and robotic approach was associated with improved survival by 12% (HR=0.88; 95%CI=0.83-0.93; p<0.0001), compared to the open approach. Similarly, the weighted adjusted 5-year overall survival was 73.1% (95%CI=72%-74.2%), 76.4% (95%CI=75.1-77.7%), and 75.5% (95%CI=74.7-76.4%) for open, laparoscopic, and robotic approaches, respectively (p<0.001).
Conclusion:
Minimally invasive surgery improved overall survival in women over 65 years with endometrial cancer.
