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Prostatic Schwannoma Presenting with Prostate-specific Antigen Elevation: A Case Report.

Benjamin Chung Howe Lai^1,2, Hung-Jen Shih^3,4,5, Syuan-Hao Syu^1,2

¹Department of Urology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.

The Yale Journal of Biology and Medicine

|December 31, 2021

Summary

This summary is machine-generated.

Prostatic schwannoma is a rare tumor that can present with elevated prostate-specific antigen (PSA). Conservative management with close observation may be a viable long-term treatment option for this uncommon condition.

Keywords:

Prostate Prostate-specific antigen Schwannoma

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Area of Science:

Urology
Oncology
Pathology

Background:

Schwannomas are rare tumors of the male genital system, typically treated surgically.
Prostatic schwannoma is exceptionally uncommon, with few cases reported in medical literature.

Observation:

A 65-year-old male presented with an elevated prostate-specific antigen (PSA) level.
Digital rectal examination and transrectal ultrasonography revealed a nodule in the left peripheral lobe of the prostate.
Histopathological analysis of the biopsy confirmed prostatic schwannoma.

Findings:

The patient opted for conservative treatment with regular image follow-up over surgery.
Over a 6-year follow-up, mild PSA progression was noted, but symptoms did not worsen.
This case highlights PSA elevation as a potential, albeit rare, presenting sign of prostatic schwannoma.

Implications:

Conservative management with vigilant monitoring may be a feasible alternative to surgery for select cases of prostatic schwannoma.
Long-term survivorship can be achieved with non-surgical approaches for rare prostatic tumors.
Elevated PSA should prompt consideration of rare diagnoses like schwannoma in the differential diagnosis.