Related Experiment Video
Updated: Jun 22, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Coronary bypass surgery in exercise-induced ventricular tachycardia
Coronary artery bypass surgery effectively treated severe exercise-induced arrhythmias in a subset of patients. This intervention improved exercise capacity and eliminated arrhythmias, suggesting bypass surgery
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Severe ischemia during exercise can precipitate serious ventricular arrhythmias.
- Exercise-induced arrhythmias pose a significant clinical challenge, sometimes leading to cardiac arrest.
- Conventional isolated bypass surgery is a common treatment for coronary artery disease.
Purpose of the Study:
- To evaluate the therapeutic effect of isolated bypass surgery on severe exercise-induced ventricular arrhythmias.
- To assess the impact of bypass surgery on exercise capacity and recurrence of arrhythmias in affected patients.
Main Methods:
- Retrospective analysis of 9 patients with severe exercise-induced ischemia and ventricular arrhythmias undergoing isolated bypass surgery.
- Clinical and electrocardiographic monitoring before and after surgery.
- Follow-up observation for up to four and a half years.
Main Results:
- All 9 patients were free of angina and anti-anginal drugs postoperatively.
- Significant increases in exercise capacity and maximal heart rate were observed.
- No recurrence of spontaneous or exercise-induced arrhythmias during the follow-up period.
Conclusions:
- Ischemia appears to be the primary factor inducing arrhythmias in this patient subset.
- Isolated bypass surgery demonstrated a therapeutic benefit for severe exercise-induced arrhythmias.
- Reduction in ischemic arrhythmias may contribute to the overall mortality benefit observed with bypass surgery.
More Related Videos
06:57Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
Published on: January 31, 2019
05:25Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome IV: Interprofessional Care
Cardiomyopathy VII: Pre and Post Operative Nursing Management