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Updated: Oct 8, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Idiopathic Sclerosing Mesenteritis: An Extremely Rare Cause of Mesenteric Mass
Samyak Dhruv1, Meena Kashi2, Dhwani Pandya3
1Depatment of Internal Medicine, Medstar St. Mary's Hospital, Leonardtown, MD, USA.
Abstract:
Idiopathic sclerosing mesenteritis (ISM) is an extremely rare condition in which mesenteric adipose tissue undergoes necrotic and fibrotic changes. It is also known as "retractile mesenteritis", "mesenteric panniculitis" or "fat necrosis of the mesentery". Most cases are seen in Caucasian males between the fifth and seventh decades of life. Some of the suggested causes of this extremely rare condition include autoimmune disorders, abdominal trauma, malignancy, abdominal infections and even IgG4-related diseases; however, the actual cause remains unknown. Most cases are either self-limiting or improve with medical therapy. However, aggressive cases requiring emergent surgical interventions to relieve intestinal obstruction have been reported in the literature. We present a case of a 60-year-old male patient who presented to the emergency room with severe abdominal pain and was diagnosed with ISM that required surgical intervention to relieve the symptoms.
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