Ultrahigh field brain magnetic resonance imaging using semiadiabatic radiofrequency pulses

Great attention is being paid to solving, or mitigating, the technical problems associated with MRI at ultrahigh field strengths of 7 T and higher. This paper explores the use of the semiadiabatic spin-echo (SA-SE) pulse sequence, which uses semiadiabatic radiofrequency (RF) pulses to remove and/or mitigate the effects of the nonuniform B₁ excitation field and B₀ inhomogeneity associated with the electromagnetic properties of the human brain. A semiadiabatic RF pulse version of the recently published serial transmit excitation pulse (STEP) RF pulse sequence is also presented that now incorporates semiadiabatic pulses, henceforth is called SA-STEP. As demonstrated by computer simulation, and confirmed using head imaging, both techniques can produce multislice SE MR imaging at 7 T. These new methods use relatively low RF power and achieve good coverage of the human brain in a single scan.