Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

16.7K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
16.7K
Causality in Epidemiology01:21

Causality in Epidemiology

1.0K
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.0K
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

223
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
223
Global Regulatory Systems01:28

Global Regulatory Systems

107
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
107
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.5K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.5K
Viral Mutations00:36

Viral Mutations

34.5K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
34.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Stochastic Poincaré maps for a slow-fast system with white noises: Approximation and visualization.

Chaos (Woodbury, N.Y.)·2026
Same journal

On a stable torus in a 3D system with a saddle-focus.

Chaos (Woodbury, N.Y.)·2026
Same journal

Targeted interventions suppress epidemic outbreaks in spatial higher-order activity-driven networks.

Chaos (Woodbury, N.Y.)·2026
Same journal

Erratum: "Hierarchical organization of bursty trains in event sequences" [Chaos 35, 113115 (2025)].

Chaos (Woodbury, N.Y.)·2026
Same journal

Deterministic control of CW/CCW alternation by dual-frequency injection in a heterogeneous oscillator ring.

Chaos (Woodbury, N.Y.)·2026
Same journal

A CTRW-driven subdiffusive fractional Brownian bridge in the reconstruction of missing experimental data.

Chaos (Woodbury, N.Y.)·2026

Related Experiment Video

Updated: Oct 8, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
08:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

3.0K

SARS-CoV-2 emerging complexity and global dynamics.

Francesca Bertacchini1, Pietro S Pantano2, Eleonora Bilotta2

  • 1Department of Mechanical, Energy and Management Engineering, University of Calabria, Cubo 43, 5th floor, Ponte P. Bucci, 87036 Arcavacata di Rende, Cosenza, Italy.

Chaos (Woodbury, N.Y.)
|January 1, 2022
PubMed
Summary

This study reveals the complex space-time patterns of SARS-CoV-2 dynamics, identifying virus phase transitions and behaviors like cluster formation. These findings offer new insights into viral dynamics for improved pandemic response.

More Related Videos

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.4K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.3K

Related Experiment Videos

Last Updated: Oct 8, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
08:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

3.0K
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.4K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.3K

Area of Science:

  • Virology
  • Complex Systems Science
  • Epidemiology

Background:

  • The SARS-CoV-2 virus exhibits complex dynamics and variations within hosts and ecosystems.
  • The spatio-temporal manifestations of SARS-CoV-2 behavior are not fully understood.
  • Understanding viral dynamics is crucial for effective pandemic management.

Purpose of the Study:

  • To analyze the global space-time patterns of SARS-CoV-2 infected individuals.
  • To quantitatively measure transitions in viral dynamical behaviors.
  • To investigate virus phase transitions and morphogenesis processes.

Main Methods:

  • Utilized 4D and 2D space-time pattern analysis of infected individuals.
  • Employed pattern slicing to identify virus behaviors such as cluster formation and bifurcation.
  • Applied entropy analysis to study morphogenesis and detect virus phase transitions.

Main Results:

  • Revealed global space-time patterns of SARS-CoV-2 infection rates.
  • Quantified transitions between different dynamical behaviors of the virus.
  • Identified virus phase transitions and morphogenesis, characteristic of adaptive biological systems.

Conclusions:

  • This research provides the first quantitative description of global SARS-CoV-2 patterning behavior.
  • The applied methods offer advantages for analyzing viral behavior within a systems biology framework.
  • Further analysis is needed, but these findings can enhance pandemic problem-solving and knowledge expansion.