Related Experiment Video
Updated: Oct 8, 2025

Measurement of Ultrafast Vibrational Coherences in Polyatomic Radical Cations with Strong-Field Adiabatic Ionization
Published on: August 6, 2018
Negligible rate enhancement from reported cooperative vibrational strong coupling catalysis
Garret D Wiesehan1, Wei Xiong1
1Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California 92093, USA.
Abstract:
We report the results of an attempt to reproduce a reported cavity catalysis of the ester hydrolysis of para-nitrophenyl acetate due to vibrational strong coupling. While we achieved the same light-matter coupling strength and detuning, we did not observe the reported ten-fold increase in the reaction rate constant. Furthermore, no obvious detuning dependence was observed. The inconsistency with the reported literature suggests that cavity catalysis is sensitive to experimental details beyond the onset of vibrational strong coupling. This indicates that other important factors are involved and have been overlooked so far. We find that more investigation into the limits, key factors, and mechanisms to reliably actualize cavity modified reactions is needed.
More Related Videos
08:40Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production
Published on: December 6, 2021
05:51Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
Published on: July 19, 2019
Related Concept Videos
¹H NMR: Long-Range Coupling
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene...
Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)
The extent of coupling depends on the C‑C bond length, the two H‑C‑C angles, any electron-withdrawing substituents, and the dihedral angle between the...
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
Spin–Spin Coupling: One-Bond Coupling
Cooperative Allosteric Transitions
Introduction to Mechanisms of Enzyme Catalysis