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Intervention Strategies to Reduce Surgical Site Infection Rates in Patients Undergoing Rectal Cancer Surgery
Masamichi Okada1, Kazushige Kawai2, Kazuhito Sasaki2
1Department of Surgical Oncology, The University of Tokyo, Tokyo, Japan okadam-sur@h.u-tokyo.ac.jp.
Background/Aim:
This study aimed to determine the effectiveness of surgical site infection (SSI) prevention approaches in rectal cancer surgery.
Patients And Methods:
A total of 1,408 patients who underwent elective rectal cancer surgery between 1995 and 2017 were reviewed. Patients were divided into three groups: control group (group A, n=245), SSI prevention intervention group (group B, n=516), and laparoscopic or robotic surgery group (group C, n=647). The groups were compared in terms of SSI and anastomotic leakage (AL) incidences, and risk factors for SSI were investigated.
Results:
The overall SSI and AL rates were 19.4% and 3.6%, respectively. These rates were significantly lower in Group C (9.3%, 1.7%), compared to Groups A (40.0%, 6.1%) and B (22.5%, 3.5%). Abdominoperineal resection, open surgery, operation time, intraoperative bleeding, lack of absorbable sutures, lack of mechanical bowel preparation, and lack of oral antibiotics were independently associated with SSI.
Conclusion:
SSI reduction after rectal cancer surgery was achieved through various intervention strategies.
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