Histamine in the human eye
Related Experiment Video
Updated: Oct 21, 2026

Glutamate and Hypoxia as a Stress Model for the Isolated Perfused Vertebrate Retina
Published on: March 22, 2015
Abstract:
Various ocular structures (iris, ciliary body, choroid, retina, sclera, optic nerve) were enucleated from human eyes suffering endophthalmitis, perforative wounds of cornea and/or sclera, or uncontrolled glaucoma, and were tested for their histamine content. All of the tested tissues contained histamine with the highest and the lowest values always found in the uvea and retina, respectively. The eyes of the 'endophthalmitis' group showed histamine levels 5-10 times higher than amine levels found in the traumatized eyes, whereas the eyes of the 'glaucoma' group were characterized by intermediate amine contents.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Anatomy of the Eyeball
Allergic Reactions: Anaphylaxis
Microbiome of the Eye

