Related Experiment Video
Updated: Oct 8, 2025

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
Published on: November 5, 2019
Scattering of a Laser Beam on an Ensemble of Asymmetrical Erythrocytes
S Yu Nikitin1, V D Ustinov2, E G Tsybrov3
1Faculty of Physics, Moscow State University, 119991 Moscow, Russia.
Abstract:
The study describes an analytical model of laser beam scattering on an inhomogeneous ensemble of erythrocytes. The model takes into account erythrocyte variation in size, shape, and spatial orientation. A relationship is established between an experimentally determined parameter: visibility of the diffraction pattern, and a characteristic serving as a measure of inhomogeneity of erythrocyte size and shape in a blood specimen. This relationship is shown to be monotonous, which means that erythrocyte variation in size and shape can be assessed based on measurements of the diffraction pattern visibility.

