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Digital Image Analysis Tools Developed by the Indiana O'Brien Center
1Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, United States.
Frontiers in Physiology
|January 3, 2022
Summary
Biomedical researchers can now analyze complex biological images with new software. The Indiana O'Brien Center developed accessible tools for intravital microscopy and organ-level analysis.
Area of Science:
- Biological Imaging
- Biomedical Research
- Microscopy
Background:
- Biological image complexity has surged, driven by advances like multiphoton microscopy.
- Intravital microscopy now offers in vivo cell biology insights.
- Optical sectioning and tissue clearing enable subcellular resolution organ characterization.
- Multiplexed imaging allows simultaneous localization of numerous probes.
Purpose of the Study:
- To describe biomedical image analysis software developed by the Indiana O'Brien Center.
- To provide robust and accessible tools for researchers navigating complex biological imaging.
Main Methods:
- Development of specialized biomedical image analysis software.
- Focus on tools for intravital microscopy and high-resolution organ imaging.
Main Results:
- The Indiana O'Brien Center has created image analysis software over 25 years.
- The software aims to simplify complex image analysis for biomedical researchers.
Conclusions:
- Accessible image analysis tools are crucial for modern biological research.
- The developed software empowers researchers to utilize advanced microscopy techniques.