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Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

170
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Esophageal Varices-I: Introduction01:24

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Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
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Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

45
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
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Related Experiment Video

Updated: Oct 8, 2025

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

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Localizing spontaneously hemostatic colonic diverticular bleeding using VISCOCLEAR gel: A case report.

Daisuke Suto1, Masashi Yoshida2, Takaaki Otake1

  • 1Department of Gastroenterology, International University of Health and Welfare Hospital, 537-3 Iguchi, Nasushiobara, Tochigi, 329-2763, Japan.

Annals of Medicine and Surgery (2012)
|January 3, 2022
PubMed
Summary

VISCOCLEAR, a novel gel, successfully located colonic diverticular bleeding when standard methods failed. This endoscopic approach improved visualization, enabling precise hemostatic clipping for gastrointestinal bleeding management.

Keywords:
Colonic diverticular bleedingColonoscopyGastrointestinal bleedingHemostatic clippingVISCOCLEAR

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Area of Science:

  • Gastroenterology
  • Endoscopy
  • Medical Devices

Background:

  • Colonic diverticular bleeding is a frequent cause of lower gastrointestinal hemorrhage.
  • Identifying the specific bleeding diverticulum can be challenging during colonoscopy.

Observation:

  • An 82-year-old male presented with melena due to colonic diverticular bleeding.
  • Standard water-assisted colonoscopy failed to identify the bleeding source.
  • Enhanced computed tomography revealed multiple diverticula.

Findings:

  • Endoscopic injection of VISCOCLEAR, a novel gel formulation, successfully localized the bleeding diverticulum.
  • VISCOCLEAR provided a clear endoscopic visual field with reduced glare.
  • Hemostatic clipping was performed after successful localization.

Implications:

  • VISCOCLEAR offers a potential solution for difficult-to-localize diverticular bleeding.
  • This technique may improve the efficacy of endoscopic interventions for gastrointestinal bleeding.
  • Further case series analysis is warranted to confirm VISCOCLEAR's effectiveness.