Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

258
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
258
Computed Tomography01:10

Computed Tomography

6.9K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
6.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bone-sparing chemoradiotherapy for anal cancer - Results of a phase II trial by the Danish Anal Cancer Group - The DACG II (NCT05385250).

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients-Final Results of the Phase II Feasibility Study TEDDI.

Pediatric blood & cancer·2026
Same author

In vivo dosimetry with an inorganic scintillation detector during multi-channel vaginal cylinder pulsed dose-rate brachytherapy: Dosimetry for pulsed dose-rate brachytherapy.

Physics and imaging in radiation oncology·2024
Same author

Dose comparison of robustly optimized intensity modulated proton therapy (IMPT) vs IMRT and VMAT photon plans for testicular seminoma.

Acta oncologica (Stockholm, Sweden)·2023
Same author

Corrigendum to "Two compound techniques for total body irradiation" [Tech. Innov. Patient Support Radiat. Oncol. 21 (2022) 1-7].

Technical innovations & patient support in radiation oncology·2023
Same author

Accuracy and potential improvements of surface-guided breast cancer radiotherapy in deep inspiration breath-hold with daily image-guidance.

Physics in medicine and biology·2022

Related Experiment Video

Updated: Oct 8, 2025

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

14.4K

Two compound techniques for total body irradiation.

Anders T Hansen1, Hanne K Rose2, Esben S Yates1

  • 1Department of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.

Technical Innovations & Patient Support in Radiation Oncology
|January 3, 2022
PubMed
Summary
This summary is machine-generated.

The ExVMAT technique significantly improves radiation dose distribution for total body irradiation (TBI) compared to ExIMRT. This advanced method enhances treatment quality without increasing time or lung dose rates.

Keywords:
IMRTRILITotal body irradiationTreatment planningVMAT

More Related Videos

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.5K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.9K

Related Experiment Videos

Last Updated: Oct 8, 2025

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

14.4K
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.5K
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.9K

Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Cancer Therapy

Background:

  • Total body irradiation (TBI) is crucial in stem cell transplantation protocols.
  • Ensuring high-quality TBI is essential for patient outcomes.
  • Two distinct TBI planning and delivery techniques are evaluated.

Purpose of the Study:

  • To compare the dosimetric efficacy of two TBI techniques: ExIMRT and ExVMAT.
  • To assess the impact of each technique on dose distribution and organ coverage.
  • To determine which technique offers superior dose distribution for TBI.

Main Methods:

  • Dosimetric data from 32 patients were analyzed.
  • ExIMRT combines manually shaped fields and IMRT fields from an extended SSD.
  • ExVMAT integrates conventional, IMRT, and VMAT fields from an extended SSD and isocentric VMAT.

Main Results:

  • ExVMAT significantly reduced overdosed volume by 120% (408 to 12 cm³).
  • ExVMAT improved lung dose coverage (9.7 to 10.3 Gy) and reduced kidney dose (12.8 to 12.5 Gy).
  • ExVMAT decreased population variance in dose distribution to organs at risk without compromising treatment time or lung dose rate.

Conclusions:

  • ExVMAT provides a superior dose distribution for TBI compared to ExIMRT.
  • The ExVMAT technique offers benefits from both individual patient and population perspectives.
  • ExVMAT represents an advancement in TBI planning and delivery.