Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Perfusion pressure and human kidney preservation.

G Murata, S I Cho

    Transplantation
    |May 1, 1978
    PubMed
    Summary

    Lowering systolic pressure during kidney preservation may reduce damage. Kidneys perfused at 55 mm Hg showed similar outcomes to those at 60 mm Hg, suggesting improved preservation quality.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clinical analysis of acute peripheral facial palsy in older adults.

    The Journal of laryngology and otology·2022
    Same author

    Radiological dimensions of the Eustachian tube in patients with adhesive otitis media.

    The Journal of laryngology and otology·2022
    Same author

    Bidirectional association between psoriasis and inflammatory bowel disease in a paediatric population: a nationwide study in South Korea.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2022
    Same author

    Pilot study of fractional microneedling radiofrequency for hidradenitis suppurativa assessed by clinical response and histology.

    Clinical and experimental dermatology·2021
    Same author

    Association of COVID-19 with skin diseases and relevant biologics: a cross-sectional study using nationwide claim data in South Korea.

    The British journal of dermatology·2020
    Same author

    Perceptions and attitudes of medical students regarding artificial intelligence in dermatology.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2020

    Area of Science:

    • Nephrology
    • Transplantation Immunology
    • Surgical Technology

    Background:

    • Kidney preservation is crucial for successful transplantation.
    • Continuous pulsatile perfusion is a standard preservation method.
    • Optimizing perfusion pressure may enhance organ viability.

    Purpose of the Study:

    • To compare the efficacy of two continuous pulsatile perfusion pressure protocols for kidney preservation.
    • To evaluate the impact of adjusted lower systolic pressure on kidney graft outcomes.

    Main Methods:

    • 708 kidneys were divided into two groups for preservation via continuous pulsatile perfusion.
    • Group 1: Maintained at a constant systolic pressure of 60 mm Hg.
    • Group 2: Initial systolic pressure of 60 mm Hg, adjusted to 55 mm Hg after 1 hour.

    Main Results:

    • Group 2 donors were younger, and kidneys were preserved longer.
    • Discard and non-function rates were equivalent between groups.
    • Group 2 exhibited a non-statistically significant higher incidence of immediate graft function.

    Conclusions:

    • Kidneys can be preserved at lower systolic and mean pressures without compromising quality.
    • Lower perfusion pressures may potentially reduce organ damage during preservation.
    • Adjusted lower pressure perfusion (55 mm Hg) shows comparable or potentially improved outcomes to constant higher pressure (60 mm Hg).

    Related Experiment Videos