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Updated: Oct 8, 2025

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
Published on: January 20, 2022
CT of transposition of the great arteries in adults
A Panayiotou1, S Thorne2, L E Hudsmith3
1Department of Radiology, King's College Hospital, London, UK.
Insights
Transposition of the great arteries (TGA) is a common congenital heart defect. Surgical advances allow TGA patients to live longer, requiring radiologists to understand postoperative imaging and long-term complications.
Area of Science:
- Cardiology
- Radiology
- Pediatric Medicine
Background:
- Transposition of the great arteries (TGA) is a frequent cyanotic congenital heart disease.
- Historically, TGA was associated with poor life expectancy, but surgical and medical advancements have improved survival into adulthood.
- Increased adult survival necessitates greater familiarity with TGA management among healthcare professionals.
Purpose of the Study:
- To familiarize general radiologists with the postoperative anatomy of TGA.
- To describe the cross-sectional imaging appearance of corrected TGA.
- To outline potential long-term complications in adult TGA patients.
Main Methods:
- Review of relevant medical literature on TGA.
- Analysis of cross-sectional imaging findings in postoperative TGA patients.
- Synthesis of information on long-term complications.
Main Results:
- Detailed description of expected postoperative anatomy following TGA repair.
- Illustrative examples of cross-sectional imaging findings.
- Identification of common and significant long-term complications.
Conclusions:
- Radiologists will encounter more adult patients with TGA due to improved survival.
- Understanding postoperative anatomy and imaging is crucial for accurate diagnosis.
- Awareness of long-term complications aids in comprehensive patient care.
Abstract:
Transposition of the great arteries is one of the most common cyanotic congenital heart diseases. It is characterised by an abnormal connection of the ventricles and great arteries, so that the aorta arises from the morphological right ventricle and the pulmonary artery arises from the morphological left ventricle. Historically, as with many congenital heart diseases, patients with transposition of the great arteries had poor life expectancy. Advances in surgical and medical management have resulted in patients surviving into adulthood. As these patients are living longer, they will be encountered more frequently in practice. The purpose of this article is to familiarise the general radiologist with the expected postoperative anatomy, and the appearance on cross-sectional imaging as well as the long-term complications in this group of patients.
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