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COMBED: Rapid non-invasive Cardiac Output Monitoring Baseline assessment in adult Emergency Department patients with
Christopher T Eyeington1,2, Emmanuel Canet1, Salvatore L Cutuli1
1Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia.
Insights
Rapid, non-invasive cardiac output monitoring (COM) is feasible in over 90% of emergency department patients with hemodynamic instability. This technology offers early insights into circulation, identifying lower cardiac index in hypotension and lower systemic vascular resistance index in suspected infection.
Area of Science:
- Emergency Medicine
- Cardiovascular Physiology
- Medical Technology
Background:
- Hemodynamic instability (HI) in emergency department (ED) patients requires timely physiological assessment.
- Non-invasive cardiac output monitoring (COM) offers potential for rapid, operator-independent data acquisition.
- Early physiological data can guide management of critically ill patients.
Purpose of the Study:
- To assess the feasibility of non-invasive COM in ED patients with HI.
- To measure baseline cardiac index (CI) and other hemodynamic parameters.
- To evaluate the utility of COM for early physiological assessment.
Main Methods:
- Prospective observational study in an ED setting.
- Non-invasive COM applied for 5 minutes to adults with tachycardia or hypotension.
- Recorded CI, mean arterial pressure (MAP), stroke volume index (SVI), and systemic vascular resistance index (SVRI).
Main Results:
- Feasible COM in >90% of patients (46/49).
- Hypotension/tachycardia group showed lower MAP, CI, and heart rate compared to tachycardia alone.
- Suspected infection group exhibited lower SVRI.
Conclusions:
- Non-invasive COM is feasible and effective in ED patients with HI.
- Distinct hemodynamic profiles identified in hypotension versus tachycardia alone.
- COM provides valuable early insights into circulatory status in critical care settings.
Objective:
The application of rapid, non-operator-dependent, non-invasive cardiac output monitoring (COM) may provide early physiological information in ED patients with haemodynamic instability (HI). Our primary objective was to assess the feasibility of measuring pre-intervention (baseline) cardiac index (CI) and associated haemodynamic parameters.
Methods:
We performed a prospective observational study of adults shortly after presentation to the ED of a large university hospital with tachycardia or hypotension or both. We applied non-invasive COM for 5 min and recorded CI, mean arterial pressure (MAP), stroke volume index (SVI) and systemic vascular resistance index (SVRI). We assessed for differences between those presenting with hypotension or hypotension and tachycardia with tachycardia alone and between those with or without suspected infection.
Results:
We obtained haemodynamic parameters in 46 of 49 patients. In patients with hypotension or hypotension and tachycardia (n = 15) rather than tachycardia alone (n = 31), we observed a lower MAP (60.8 vs 87.7, P < 0.0001), CI (2.8 vs 3.9, P = 0.0167) and heart rate (85.5 vs 115.4, P < 0.0001). There was no difference in SVI (33.7 vs 33.4, P = 0.93) or SVRI (1970 vs 2088, P = 0.67). Patients with suspected infection had similar haemodynamic values except for a lower SVRI (1706 vs 2237, P = 0.011).
Conclusions:
Rapid, non-operator-dependent, non-invasive COM was possible in >90% of ED patients presenting with HI. Compared with tachycardia alone, patients with hypotension had lower CI, MAP and heart rate, while those with suspected infection had a lower SVRI. This technology provides novel insights into the early state of the circulation in ED patients with HI.
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