Double Balloon Enteroscopy in a Pregnant Woman with Peutz-Jeghers Syndrome

Mesut Akarsu1, Soner Onem1, Zarni Htway1

  • 1Department of Gastroenterology, Dokuz Eylul University School of Medicine, Izmir, Turkey.

Insights

Peutz-Jeghers syndrome patients can safely undergo double balloon enteroscopy during pregnancy. This procedure successfully removed obstructive polyps, preventing complications in a pregnant patient.

Area of Science:

  • Gastroenterology
  • Genetics

Background:

  • Peutz-Jeghers syndrome (PJS) is an inherited disorder causing hamartomatous polyps and mucocutaneous pigmentation.
  • Polyps commonly occur in the small intestine, particularly the jejunum, posing risks of obstruction and intussusception.

Observation:

  • A pregnant woman with PJS and prior intestinal surgery presented with concerning polyp burden.
  • Termination was initially advised due to potential pregnancy complications from polyps.

Findings:

  • Double balloon enteroscopy was successfully performed in the second trimester of pregnancy.
  • Large, potentially obstructive polyps were removed, and post-polypectomy bleeding was managed effectively.
  • This represents the first reported instance of double balloon enteroscopy during pregnancy for PJS management.

Implications:

  • Double balloon enteroscopy is a viable option for managing PJS-related polyps during pregnancy.
  • The procedure requires experienced endoscopists in specialized centers due to inherent risks.
  • Timely intervention can prevent serious complications in pregnant PJS patients.