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A case of Bartonella henselae native valve endocarditis presenting with crescentic glomerulonephritis

Roshni Patel1, Kansas Koran1, Mark Call1

  • 1Prisma Health Infectious Disease Specialists, 890 West Faris Road, Suite 520, Greenville, SC 29605, USA.

Idcases
|January 5, 2022
PubMed

Insights

Bartonella henselae endocarditis is difficult to diagnose, often presenting as renal failure. Next-generation sequencing offers a faster method for identifying this destructive infection.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Nephrology

Background:

  • Bartonella endocarditis diagnosis is challenging, relying on multiple tests and symptom assessment.
  • Bartonella henselae, a cause of endocarditis, is difficult to culture, leading to diagnostic delays.

Observation:

  • A case of Bartonella henselae native mitral valve endocarditis presented with volume overload and renal failure.
  • The organism's slow growth in culture complicates early identification.

Findings:

  • The destructive nature of Bartonella henselae endocarditis necessitates rapid identification.
  • Next-generation sequencing (NGS) presents a potential solution for timely diagnosis.

Implications:

  • Increased clinician awareness of Bartonella henselae endocarditis is crucial for cases with acute renal failure and culture-negative vegetations.
  • NGS may improve diagnostic speed and patient outcomes for Bartonella endocarditis.

Keywords:
BartonellaCrescentic glomerulonephritisCulture negative endocarditisNext Generation Sequencing

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