Gene transfer experiments to study T-cell recognition of MHC and antigen

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Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT
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Published on: September 30, 2010

M Steinmetz, Z Dembic

    Behring Institute Mitteilungen
    |June 1, 1987
    PubMed

    Gene transfer experiments are discussed which demonstrate the following: First, MHC-restricted antigen specificities of T lymphocytes are encoded by the alpha and beta T-cell receptor genes. Second, the interaction between cytotoxic T lymphocytes and their target cells is enhanced by the Lyt 2 molecule.

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