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Updated: Oct 7, 2025
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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
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Emergency Department Utilization and Serious Bacterial Infection Rates in Children With Renal Transplants.
Jason King, Nirupama Kannikeswaran, Amrish Jain
1Department of Pediatrics, Wayne State University School of Medicine.
Pediatric Emergency Care
|January 6, 2022
Summary
Pediatric renal transplant patients most frequently present with infections, primarily urinary tract infections (UTIs), which are the most common serious bacterial infection (SBI). Bacteremia and severe interventions were rare in this cohort.
Area of Science:
- Pediatric Nephrology
- Transplant Medicine
- Infectious Diseases
Background:
- Emergency department (ED) visits for children with solid organ transplants are increasing.
- Understanding common presentations and infections in pediatric renal transplant (RT) recipients is crucial for timely management.
Purpose of the Study:
- To describe common chief complaints, diagnoses, and rates of serious bacterial infection (SBI) in pediatric renal transplant patients presenting to the hospital.
Main Methods:
- Retrospective study of pediatric RT patients (up to 18 years) presenting to the ED or admitted from 2012-2016.
- Data collected included demographics, transplant details, chief complaints, diagnostic tests, interventions, and final diagnoses.
- Excluded patients presenting for procedures.
Main Results:
- Analyzed 131 visits from 29 patients; most common complaints were infectious (34.4%) and gastrointestinal (26%).
- Serious bacterial infection (SBI) occurred in 26.0% of visits, with urinary tract infection (UTI) being most common (20.6%).
- Among fever visits, 48.5% had SBI, predominantly UTI (30.3%). Bacteremia and hypotension were rare.
Conclusions:
- Pediatric RT patients most commonly present with infections, with UTI as the leading SBI.
- Bacteremia and need for significant interventions were infrequent.
- Further research is needed to identify low-risk pediatric RT patients eligible for ED discharge.
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