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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Post-infectious ST elevation myocardial infarction following a COVID-19 infection: A case report
Manuela Ceccarelli1, Andrea Marino1, Federica Cosentino1,2
1Unit of Infectious Diseases, ARNAS Garibaldi, Nesima Hospital, Department of Clinical and Experimental Medicine, University of Catania, I-95122 Catania, Sicily, Italy.
Insights
This case report details a patient with COVID-19 who experienced a heart attack, specifically ST-segment elevation myocardial infarction (STEMI). It suggests a link between SARS-CoV-2 infection and acute coronary syndrome, possibly due to inflammation and hypoxemia.
Area of Science:
- Cardiology
- Infectious Diseases
- Pulmonology
Background:
- Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) infection is associated with a hypercoagulable state, increasing thrombotic event risk.
- Pre-existing conditions like hypertension and metabolic disorders can exacerbate COVID-19 complications.
Observation:
- A 59-year-old woman with hypertension and metabolic disorders developed cardiac symptoms during COVID-19 hospitalization.
- Electrocardiogram and cardiac ultrasound confirmed ST-segment elevation myocardial infarction (STEMI).
Findings:
- The patient successfully underwent percutaneous coronary intervention for STEMI.
- This case suggests a potential association between SARS-CoV-2 infection and acute coronary syndrome.
Implications:
- The link between SARS-CoV-2 and cardiovascular events may involve proinflammatory states and hypoxemia.
- Further research is needed to understand the long-term cardiovascular sequelae of COVID-19.
Abstract:
Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has been shown to increase the risk of thrombotic events due to a hypercoagulable state caused by several factors. The case of a 59-year-old woman affected by hypertension and metabolic disorders, treated for a COVID-19 infection who developed cardiac symptoms during the first days of hospitalization is reported. Electrocardiogram analysis and cardiac-ultrasound confirmed ST-segment elevation myocardial infarction (STEMI) diagnosis, thus the patient underwent percutaneous coronary intervention, which was successful. This case highlights a possible association between respiratory infection, particularly SARS-CoV-2 infection, and cardiovascular events, in particular Acute Coronary Syndrome. The association between these phenomena seems related to a range of factors, including a proinflammatory state and the hypoxemia. Moreover, the association amongst SARS-CoV-2 and cardiovascular diseases may be also linked to long-term sequelae. Thus, further studies are required to better understand the multifaceted and severe complications of this disease.
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