[Secondary immunologic deficiency and its correction in cancer patients after radiation and combined therapy]

The problems of radiation immunology in oncological practice are discussed using, by way of example, studies on the effect of radiation and combined therapy on the state of the immunity system in some cancer types. The authors present data on the development of secondary immunodeficiency states determined by disorder in lymphocyte level, cooperation, enzymatic properties and function in immune reactions. A possibility of correction of secondary immunodeficiency states after radiation and combined therapy with the help of immunomodulators was shown.