Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronic pruritus treated with alendronate in bilateral striopallidodentate calcinosis associated with an SLC20A2 gene mutation.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

Optimal Formalin-Fixed Paraffin-Embedded Sample Preservation for Efficient Staining in Multiplex Imaging.

Laboratory investigation; a journal of technical methods and pathology·2026
Same author

Development and external validation of a FDG PET-based radiomics model predicting occult lymph node metastasis in non-small cell lung cancer patients.

European journal of nuclear medicine and molecular imaging·2026
Same author

[Study of the performances of conversational agents in interpreting textual description of lesions in pathology].

Annales de pathologie·2026
Same author

The immune cell landscape analysed by imaging mass cytometry in the muscle of patients with inclusion body myositis associated or not with Sjögren's disease.

Rheumatology (Oxford, England)·2026
Same author

When Crohn's Disease Is Confined to the Mouth: A Diagnostic Challenge-A Case Report and Review of the Literature.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Oct 7, 2025

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
10:35

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

Published on: April 5, 2018

10.5K

[Rapid Idylla™ mutational testing: Current and future theranostic applications].

Amélie Bourhis1, Annabelle Remoué1, Laura Samaison2

  • 1Service d'anatomie et cytologie pathologiques, hôpital Morvan, CHRU de Brest, 5, avenue Foch, 29609 Brest, France.

Annales De Pathologie
|January 7, 2022
PubMed
Summary

The Idylla™ platform offers fast, automated molecular analysis for key cancer biomarkers like BRAF and EGFR. This real-time PCR technology aids treatment decisions in advanced cancers, including melanoma, lung, and colorectal cancers.

Keywords:
BRAFBiomarkerBiomarqueurEGFRIdylla™KRASKRAS, NRASMSINRAS

More Related Videos

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

24.6K
Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay
10:57

Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay

Published on: August 14, 2018

10.8K

Related Experiment Videos

Last Updated: Oct 7, 2025

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
10:35

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

Published on: April 5, 2018

10.5K
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

24.6K
Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay
10:57

Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay

Published on: August 14, 2018

10.8K

Area of Science:

  • Oncology
  • Molecular Diagnostics
  • Biomarker Analysis

Background:

  • Molecular analyses are crucial for guiding cancer treatment decisions in advanced stages.
  • Next-generation sequencing (NGS) and targeted non-NGS analyses are key molecular diagnostic approaches.
  • The Idylla™ platform provides rapid, automated real-time PCR for specific biomarker mutations.

Purpose of the Study:

  • To review data on the Idylla™ platform for molecular analysis of cancer biomarkers.
  • To evaluate the platform's utility in detecting mutations in BRAF, KRAS, NRAS, and EGFR, and microsatellite instability.
  • To discuss the implementation and future applications of Idylla™ in laboratory workflows.

Main Methods:

  • Review of existing data on the Idylla™ real-time PCR platform.
  • Focus on automated mutational analyses of specific genes (BRAF, KRAS, NRAS, EGFR).
  • Assessment of microsatellite instability detection capabilities.

Main Results:

  • The Idylla™ platform enables fast and fully automated real-time PCR for targeted biomarker analysis.
  • The platform is effective for analyzing key mutations in melanoma, non-small-cell lung cancer, and colorectal cancer.
  • Data supports the utility of Idylla™ in molecular diagnostics for advanced cancers.

Conclusions:

  • The Idylla™ platform is a valuable tool for rapid, automated molecular testing in oncology.
  • Its implementation can streamline workflows in pathology and molecular biology labs.
  • The platform supports critical biomarker analysis for personalized cancer treatment.