Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report
Ryan M Hess1, Asham Khan1, Mallory Edwards2
1Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Buffalo General Medical Center, Kaleida Health, Buffalo, New York, United States.
Background:
Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment.
Case Description:
We present the case of a 66-year-old man who presented with altered mental status and progressively became comatose. He was found to have fulminant ventriculitis due to a ruptured intracranial abscess. He was treated with bilateral IRRAflow® catheter (IRRAS, Stockholm, Sweden) placement through which continuous irrigation with vancomycin was initiated.
Conclusion:
This treatment was safe and led to improvement in the patient's neurologic examination, imaging findings, and cerebrospinal fluid profiles.
