Related Experiment Video
Updated: Oct 7, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
Published on: May 10, 2022
Health Within Reach-a Patient-Centered Intervention to Increase Hepatitis B Screening Among Asian Americans: a
Mandana Khalili1, Nicole J Kim2, Janice Y Tsoh3
1Division of Gastroenterology and Hepatology, University of California San Francisco, San Francisco, CA, USA. Mandana.Khalili@ucsf.edu.
A mobile app improved hepatitis B screening for Asian Americans. The multilingual Hepatitis App significantly increased patient-provider discussions and HBV testing rates in primary care settings.
Area of Science:
- Public Health
- Health Informatics
- Hepatology
Background:
- Asian Americans experience high rates of chronic hepatitis B (HBV) infection.
- Limited studies focus on interventions to increase HBV screening in this population.
- Effective strategies are needed to address this health disparity.
Purpose of the Study:
- To develop and implement a mobile application (Hepatitis App) for HBV screening.
- To test the efficacy of a multilingual mobile app in increasing HBV screening among Asian Americans.
- To evaluate the impact of technology-based interventions on viral hepatitis screening.
Main Methods:
- A cluster-randomized clinical trial was conducted.
- 452 Asian American patients aged 18+ with no prior HBV testing participated.
- The intervention group used a multilingual Hepatitis App; the control group used a nutrition/activity app.
Main Results:
- The Hepatitis App was well-received, with over 80% of users liking it.
- Intervention participants were significantly more likely to discuss HBV (70% vs. 16%) and undergo HBV testing (38% vs. 8%) within 3 months.
- Multivariable analyses showed an odds ratio of 7.6 for HBV test ordering and 7.5 for test receipt in the intervention group.
Conclusions:
- A multilingual mobile app intervention effectively increased HBV screening among Asian Americans.
- The Hepatitis App enhanced patient-provider communication regarding HBV.
- Technology-driven interventions show promise for improving healthcare quality in underserved populations.
Related Concept Videos
Bioavailability Study Design: Healthy Subjects Versus Patients
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

