Related Experiment Video For 13C

Updated: Oct 7, 2025

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

Metabolic Imaging Using Hyperpolarization for Assessment of Premalignancy

Shivanand Pudakalakatti¹, Priyank Raj^1,2, Travis C Salzillo^1,2

¹Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Methods in Molecular Biology (Clifton, N.J.)

|January 7, 2022

Abstract:

There is an unmet need for noninvasive surrogate markers that can help identify premalignant lesions across different tumor types. Here we describe the methodology and technical details of protocols employed for in vivo ¹³C pyruvate metabolic imaging experiments. The goal of the method described is to identify and understand metabolic changes, to enable detection of pancreatic premalignant lesions, as a proof of concept of the high sensitivity of this imaging modality.

Keywords:

13C Assessment of preventive responses Early detection HP-MR Hyperpolarization MRI Metabolic imaging Premalignancy

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Keywords:

13C Assessment of preventive responses Early detection HP-MR Hyperpolarization MRI Metabolic imaging Premalignancy

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