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Left eye enucleation caused by multi-systemic Klebsiella pneumoniae invasive syndrome
Yanquan Liu1, Hongquan Zhu1, Yue Yin2
1Clinical Medicine Research Center, Department of Intensive Medicine, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Abstract:
Klebsiella pneumoniae is generally considered the most common pathogenic bacterium causing community-acquired pneumonia. In recent years, cases of liver abscess caused by the bacterium and its spread have been reported in Asia and other parts of the world. This clinical symptom of liver abscess caused by hypervirulent K. pneumoniae and its migrating infection is also called invasive K. pneumoniae liver abscess syndrome (IKPLAS). This study explored the clinical characteristics, diagnosis, and treatment of an elderly patient with IKPLAS who experienced multi-organ failure caused by the infection. The treatment of the patient was difficult, and despite our efforts, the invasive infection led to eye enucleation. This paper is expected to improve our understanding and awareness of this disease in the clinic.
Insights
Invasive Klebsiella pneumoniae liver abscess syndrome (IKPLAS) is a severe infection. This case study highlights the challenges in treating IKPLAS in an elderly patient, leading to multi-organ failure and eye enucleation.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Klebsiella pneumoniae is a common cause of pneumonia.
- Increasing reports of liver abscesses caused by K. pneumoniae, termed invasive K. pneumoniae liver abscess syndrome (IKPLAS), are emerging globally.
- IKPLAS can lead to severe systemic complications.
Purpose of the Study:
- To explore the clinical characteristics, diagnosis, and treatment of IKPLAS.
- To highlight the challenges in managing severe IKPLAS cases.
- To increase clinical awareness of IKPLAS and its potential complications.
Main Methods:
- Case report of an elderly patient with IKPLAS.
- Detailed description of clinical presentation, diagnostic findings, and treatment course.
- Analysis of the patient's multi-organ failure and treatment outcomes.
Main Results:
- The patient presented with severe IKPLAS and multi-organ failure.
- Treatment was complex and ultimately unsuccessful in preventing severe sequelae.
- The invasive infection necessitated eye enucleation.
Conclusions:
- IKPLAS poses significant clinical challenges, particularly in elderly patients.
- Early recognition and aggressive management are crucial for improving outcomes.
- This case underscores the potential severity and devastating complications of IKPLAS.
