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Updated: Oct 7, 2025

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
Published on: August 30, 2012
Measuring Solute Concentration with Terahertz Time-Domain Spectroscopy in Single and Multiphase Systems
Johanna Kölbel1, Qi Li1, Terence L Threlfall2
1Department of Chemical Engineering, University of Cambridge, Cambridge CB3 0AS, United Kingdom.
Abstract:
A versatile setup based on a microfluidic platform allows investigation of liquid samples at various temperatures with terahertz time-domain spectroscopy. The setup is applied to develop a novel method that performs temperature and concentration calibrations of liquid samples at terahertz frequencies. Other than measuring the concentration of pure liquid phase solutions, it enables the studies of local concentration of semicrystalline systems. An equivalent solute concentration during crystallization can be calculated from the extracted absorption at low frequencies. The MgSO4-water system is discussed as an example to illustrate the idea of this method.
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