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Related Concept Videos

Contact-dependent Signaling01:19

Contact-dependent Signaling

Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
What are Second Messengers?01:12

What are Second Messengers?

Because many receptor binding ligands are hydrophilic, they do not cross the cell membrane and thus their message must be relayed to a second messenger on the inside. There are several second messenger pathways, each with their own way of relaying information. G-protein coupled receptors can activate both phosphoinositol and cyclic AMP (cAMP) second messenger pathways. The phosphoinositol path is active when the receptor induces phospholipase C to hydrolyze the phospholipid,...
Feedback Inhibition00:46

Feedback Inhibition

Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
Feedback Loops01:01

Feedback Loops

In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
Castigliano's Theorem01:18

Castigliano's Theorem

Castigliano's theorem analyzes displacements and rotations in elastic structures. It relates the derivative of elastic strain energy to the applied forces or moments, allowing for the calculation of deformations. The theorem states that the partial derivative of the total strain energy of a system with respect to a specific load results in the displacement at the point where the load is applied. This principle applies to both forces and moments.
The Response of Equilibria to the Conditions01:30

The Response of Equilibria to the Conditions

Named after the French chemist Henry Louis Le Chatelier, Le Chatelier's principle states that when a system at equilibrium is subjected to any change (like pressure, temperature, or concentration), the composition of the system adjusts in a way that counteracts the effect of this change, thereby attempting to restore the equilibrium.According to Le Chatelier's principle, for exothermic reactions, when the system's temperature is increased, the system will try to reduce the temperature. This...

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Corticospinal Excitability Modulation During Action Observation
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Reply to S. Cavalieri et al

Sewanti Limaye1, Prashant Kumar1, Rajan Datar1

  • 1Sewanti Limaye, MBBS, MD, MS, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, India; Prashant Kumar, PhD, Institute of Bioinformatics, Bangalore, India, Manipal Academy of Higher Education (MAHE), Manipal, India, Department of Research and Innovations, Datar Cancer Genetics Limited, Nasik, India; Rajan Datar, BE, Datar Cancer Genetics Limited, Nasik, India; and Aditya Shreenivas, MBBS, MD, MS, Department of Medical Oncology, Medical College of Wisconsin, Milwaukee, WI.

JCO Precision Oncology
|January 7, 2022
PubMed
Summary

No abstract available in PubMed .

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