Related Experiment Video

Updated: Oct 7, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

3.2K

Biopsychosocial Factors Associated with Parenting Stress in Pediatric Sickle Cell Disease

Yelena L Johnson1,2, Kerri Woodward1,2, Carlton Dampier1,3

  • 1Children's Healthcare of Atlanta, Aflac Cancer and Blood Disorders Center, Atlanta, GA, 30322, USA.

Journal of Clinical Psychology in Medical Settings
|January 7, 2022
PubMed

Insights

Parenting stress in pediatric sickle cell disease (SCD) is linked to child pain and missed school. Addressing caregiver well-being is crucial for effective SCD management and youth outcomes.

Area of Science:

  • Pediatric Hematology
  • Psychosocial Health
  • Caregiver Support

Background:

  • Caregivers of children with sickle cell disease (SCD) face substantial physical and emotional challenges.
  • Understanding the factors contributing to parenting stress in pediatric SCD is limited.

Purpose of the Study:

  • To identify child and caregiver biopsychosocial factors associated with disease-related parenting stress in pediatric SCD.
  • To explore the role of parenting stress in the relationship between child pain and healthcare utilization.

Main Methods:

  • Cross-sectional study involving 74 caregiver-youth dyads.
  • Utilized assessments of child pain frequency, missed school days, healthcare utilization, and caregiver mental health and social-emotional functioning.

Main Results:

  • Parenting stress correlated with higher child pain frequency, more missed school days, and increased healthcare utilization.
  • Parenting stress was inversely associated with caregiver mental health and social-emotional functioning.
  • Parenting stress partially mediated the link between child pain frequency and healthcare utilization, even after accounting for parent depression and anxiety.

Conclusions:

  • Parenting stress is a significant factor in pediatric SCD, impacting youth in medical and academic settings.
  • Identifying risk factors and developing interventions for parenting stress are essential for comprehensive patient care.
  • Further research is needed to fully understand and address parenting stress in pediatric SCD.

Keywords:
Chronic illnessDistressParenting stressPediatricPsychosocialSickle cell disease

More Related Videos

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents06:15

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

Published on: July 10, 2017

13.0K
Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood08:09

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood

Published on: February 11, 2017

11.6K

Related Concept Videos

Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
221
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
4.6K
Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
182
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
101
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
241
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
77