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Updated: Oct 7, 2025
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Robotic system for top to bottom MRgFUS therapy of multiple cancer types
Anastasia Antoniou1, Marinos Giannakou2, Nikolas Evripidou1
1Department of Electrical Engineering, Computer Engineering, and Informatics, Cyprus University of Technology, Limassol, Cyprus.
Background:
A robotic system for Magnetic Resonance guided Focussed Ultrasound (MRgFUS) therapy of tumours in the breast, bone, thyroid, and abdomen was developed.
Methods:
A special C-shaped structure was designed to be attached to the table of conventional magnetic resonance imaging (MRI) systems carrying 4 computer-controlled motion stages dedicated to positioning a 2.75 MHz spherically focussed transducer relative to a patient placed in the supine position. The developed system was evaluated for its MRI compatibility and heating abilities in agar-based phantoms and freshly excised tissue.
Results:
Compatibility of the system with a clinical high-field MRI scanner was demonstrated. FUS heating in the phantom was successfully monitored by magnetic resonance thermometry without any evidence of magnetically induced phenomena. Cigar-shaped discrete lesions and well-defined areas of overlapping lesions were inflicted in excised tissue by robotic movement along grid patterns.
Conclusions:
The developed MRgFUS robotic system was proven safe and efficient by ex-vivo feasibility studies.
