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Published on: July 7, 2013
Stent grafts improved patency of ruptured hemodialysis vascular accesses
Min-Tsun Liao1,2, Chien-Ming Luo2,3, Ming-Chien Hsieh1
1Division of Cardiology, Department of Medicine, National Taiwan University Hospital Hsinchu Branch, Hsinchu, Taiwan, ROC.
Insights
Stent grafts significantly improve target lesion patency for ruptured dialysis access compared to balloon tamponade. This endovascular repair method offers a durable solution, extending time to reintervention for patients undergoing dialysis access procedures.
Area of Science:
- Interventional Nephrology
- Vascular Surgery
- Medical Device Technology
Background:
- Rupture of dialysis access during percutaneous transluminal angioplasty is a complication requiring effective management.
- Traditional methods like balloon tamponade have limitations in achieving long-term patency.
- Stent grafts offer a potential alternative for sealing these ruptures.
Purpose of the Study:
- To compare the efficacy of stent graft repair versus balloon tamponade for managing ruptured dialysis access.
- To evaluate target lesion primary patency and access circuit patency at 6 and 12 months post-intervention.
Main Methods:
- Retrospective analysis of 143 patients with ruptured dialysis access from 2010-2018.
- Comparison of outcomes between 52 patients treated with stent grafts and 91 patients treated with balloon tamponade.
- Primary endpoint: target lesion primary patency at 12 months.
Main Results:
- Stent graft group showed significantly higher 6-month (66.7% vs. 29.5%) and 12-month (52.5% vs. 9.0%) target lesion primary patency.
- Stent grafts increased median time to reintervention by 171 days (260 vs. 89 days).
- No significant difference in access circuit patency rates at 6 and 12 months between the groups.
Conclusions:
- Stent grafts provide superior target lesion primary patency for ruptured dialysis access compared to balloon tamponade.
- Stent graft repair is a durable solution that prolongs the time to subsequent interventions.
- While access circuit patency was similar, stent grafts offer a significant advantage in lesion-specific outcomes.
Abstract:
This study aimed to compare stent graft with balloon tamponade for ruptured dialysis access during percutaneous transluminal angioplasty. Patients over an 8-year period (2010-2018) were identified from a database of 11,609 procedures. The primary endpoint was target lesion primary patency at 12 months. A total of 143 patients who had rupture dialysis access were enrolled, of whom 52 were salvaged by stent grafts and 91 were salvaged by balloon tamponade. The 6-month target lesion primary patency was greater in the stent graft group than in the balloon tamponade group (66.7% vs. 29.5%, P < 0.001). The benefit of stent grafts was sustained for 12 months (52.5% vs. 9.0%, P < 0.001). The stent grafts increased the median time from the index procedure to the next intervention in the ruptured area by 171 days (260 vs. 89 days) at 12 months. There was no significant difference in the access circuit patency rates at 6 months (25.5% vs. 19.8%, P = 0.203) and 12 months (12.0% vs. 5.8%, P = 0.052). The patency results of the stent grafts remained after the multivariable adjustment analysis. Compared to balloon tamponade alone, stent grafts provided superior target lesion primary patency at 6 and 12 months. The access circuit patency rates were similar.
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