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Ophthalmic zoster: mucous plaque keratitis
The British Journal of Ophthalmology
|October 1, 1987
Summary
Zoster mucous plaque keratitis (MPK) presents as greyish plaques, often with complications if delayed. Prompt treatment with steroids and acetylcysteine typically resolves MPK within a month, though surgery may be needed for severe cases.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Herpes zoster ophthalmicus can lead to severe ocular complications.
- Zoster mucous plaque keratitis (MPK) is a specific manifestation requiring characterization.
Purpose of the Study:
- To characterize the clinical presentation and behavior of zoster mucous plaque keratitis (MPK).
- To identify factors influencing MPK complications and outcomes.
Main Methods:
- Retrospective analysis of 1221 patients with MPK from Moorfields Eye Hospital Zoster Clinic over 15 years.
- Clinical data review including presentation, associated conditions, treatment, and surgical outcomes.
Main Results:
- MPK typically presents with greyish plaques, limbitis, stromal keratitis, and decreased corneal sensation.
- Associated conditions include cataracts, elevated intraocular pressure, and corneal ulceration.
- Delayed MPK onset (after 3 months) correlates with increased complications; most cases resolve within a month with topical steroids and acetylcysteine, but surgery is sometimes necessary.
Conclusions:
- MPK requires prompt diagnosis and management to prevent complications.
- Topical steroids and acetylcysteine are effective initial treatments.
- Surgical intervention for MPK-related complications like glaucoma or cataracts yields good results.