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Related Experiment Video

Updated: Oct 7, 2025

Gene Editing of Primary Rhesus Macaque B Cells
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Genomic resources for rhesus macaques (Macaca mulatta).

Jeffrey Rogers1

  • 1Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. jr13@bcm.edu.

Mammalian Genome : Official Journal of the International Mammalian Genome Society
|January 9, 2022
PubMed
Summary

This study highlights the rhesus macaque genome, a vital resource for understanding primate biology and human disease models. It reviews key online databases for accessing crucial genetic and genomic data.

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Area of Science:

  • Primate genomics
  • Comparative genomics
  • Biomedical research

Background:

  • Rhesus macaques (Macaca mulatta) are extensively studied nonhuman primates.
  • They serve as critical models for human health and disease research.
  • Genetic and genomic analyses are essential for current biological and biomedical research.

Purpose of the Study:

  • To discuss information resources for rhesus macaque genetic and genomic data.
  • To provide researchers access to genome content, variation, and gene expression data.
  • To highlight the importance of the rhesus macaque genome in scientific research.

Main Methods:

  • Review of publicly available online databases and resources.
  • Discussion of data accessibility for genetic variation and gene expression.

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  • Identification of key platforms for genomic analysis.

    • Main Results:

    • Several online databases provide comprehensive rhesus macaque genomic data.
    • Resources include the National Center for Biotechnology Information, UCSC Genome Browser, Ensembl, mGAP, and Rhesusbase.
    • These databases facilitate studies on genome content, genetic variation, and gene expression.

    Conclusions:

    • The rhesus macaque genome is well-characterized, with abundant data resources available.
    • These resources are invaluable for researchers studying primate biology and human diseases.
    • Continued exploration of these genomic datasets will advance biomedical science.