Related Experiment Video
Updated: Oct 7, 2025

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center
Rida Salman1, Andrew C Sher1, Marla B K Sammer1
1Edward B. Singleton Department of Radiology, Texas Children's Hospital, 6701 Fannin St., Suite 470, Houston, TX, 77030, USA.
Insights
COVID-19 in children can cause intussusception, with nearly half of ultrasounds showing abnormalities. While some cases required surgery, other gastrointestinal issues were more common.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Radiology
Background:
- COVID-19 can present with gastrointestinal symptoms in children.
- Intussusception is a known, though uncommon, manifestation.
- Ultrasound findings in COVID-19 associated intussusception require further characterization.
Purpose of the Study:
- To report the ultrasound findings in pediatric patients with COVID-19 and suspected intussusception.
- To determine the prevalence of abnormalities on ultrasound in this cohort.
Main Methods:
- Retrospective analysis of pediatric patients (<18 years) tested for COVID-19.
- Inclusion criteria: ultrasound for suspected intussusception between April-December 2020.
- Review of demographic, clinical, radiological, and surgical data.
Main Results:
- Twenty-four COVID-19 positive patients identified (19 males, mean age 3 years).
- Ultrasound abnormalities found in 46% (11/24) of patients.
- Ileocolic intussusception occurred in 13% (3/24), with 100% failure of air enema reduction, necessitating surgery.
Conclusions:
- Heightened awareness for intussusception in COVID-19 pediatric cases is warranted.
- Ultrasound can identify intussusception, but other GI manifestations of COVID-19 are more frequent.
- Failed air enema reduction may indicate delayed presentation.
Purpose:
COVID-19 disease can manifest with intussusception in pediatric patients, but prevalence of abnormalities on ultrasounds performed for intussusception is uncertain. We aim to report our experience in children with COVID-19 presenting with suspected intussusception imaged with ultrasound.
Methods:
Children under 18 years who had an ultrasound for possible intussusception underwent retrospective analysis and were tested for COVID-19 between April 1 and December 14, 2020. Patients' demographic, clinical, radiological and surgical characteristics were reviewed.
Results:
Twenty-four COVID-19-positive patients were identified; 19 boys with mean age 3 years (range: 3 months-18 years). Ultrasound was abnormal in 11 patients (11/24, 46%). Sonographic features of enterocolitis were documented in seven children (7/24, 29%). Three boys (3/24, 13%) were found to have ileocolic intussusception on ultrasound and underwent air enema with failed reduction (3/3, 100%), precipitating surgical reductions, all with favorable outcomes. One patient (1/24, 4%) was found to have a long segment of persistent small bowel-small bowel intussusception which was surgically repaired.
Conclusion:
Given the known association between failed reduction at air enema and delayed presentation, heightened awareness for intussusception in the setting of COVID-19 should be maintained, though more often, the etiology was attributed to other GI manifestations of COVID-19.
Related Concept Videos
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

