Clinical practice guidelines for endoscopic papillectomy

Area of Science:

• Gastroenterology
• Endoscopic Surgery
• Oncology

Background:

• Endoscopic papillectomy (EP) is an emerging therapeutic option for ampullary tumors.
• High-risk endoscopic procedures require clear clinical guidelines.
• Limited high-level evidence necessitates expert consensus for practice recommendations.

Purpose of the Study:

• To establish clinical practice guidelines for endoscopic papillectomy (EP).
• To provide a scientific framework for EP based on expert consensus.
• To address key aspects of EP, including indications, techniques, outcomes, and follow-up.

Main Methods:

• Development of guidelines by the Japan Gastroenterological Endoscopy Society.
• Scientific approach integrating expert consensus.
• Focus on five critical areas of EP: indications, preparation/technique, adverse events, outcomes, and follow-up.

Main Results:

• Guidelines cover indications for EP in ampullary tumors.
• Detailed recommendations on preoperative/intraoperative preparations and techniques are provided.
• Information on early adverse events, therapeutic outcomes, remnant/recurrent disease, and follow-up is included.

Conclusions:

• The developed guidelines offer a comprehensive framework for endoscopic papillectomy.
• These guidelines aim to standardize and improve the clinical practice of EP.
• The consensus-based approach addresses the current evidence limitations in EP.