Related Experiment Video
Updated: Oct 7, 2025

Determining Viral Disinfection Efficacy of Hot Water Laundering
Published on: June 21, 2022
Assessing changes to N95 respirator filtration efficiency, qualitative and quantitative fit, and seal check with
Christina F Yen1, Robert Seeley2, Patrick Gordon3
1Division of Infection Control/Hospital Epidemiology, Silverman Institute of Health Care Quality & Safety, Beth Israel Deaconess Medical Center, Boston, MA; Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA.
Abstract:
N95 respirators were reprocessed using vaporized hydrogen peroxide to supplement limited supplies during the COVID-19 pandemic. In this study, we found no statistically significant differences in qualitative and quantitative fit or filtration efficiency with reprocessing. Filtration efficiency remained above 95% even at 25 cycles of reprocessing without statistically significant change from cycle 20-25 compared to cycle 0 (P = .10, P = .05, respectively). Vaporous hydrogen peroxide is an effective option to augment N95 respirator supplies.
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