Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Basicity of Heterocyclic Aromatic Amines01:25

Basicity of Heterocyclic Aromatic Amines

6.3K
Heterocyclic amines, where the N atom is a part of an alicyclic system, are similar in basicity to alkylamines. Interestingly, the heterocyclic amine having a nitrogen atom as part of an aromatic ring has much less basicity than its corresponding alicyclic counterpart. For this reason, as presented in Figure 1, piperidine (pKb = 2.8) is significantly more basic than pyridine (pKb = 8.8).
6.3K
Applications of IR Spectroscopy: Overview01:11

Applications of IR Spectroscopy: Overview

1.3K
The non-destructive nature and ability to provide valuable chemical information make IR spectroscopy a versatile technique with broad applications in various scientific and industrial fields. IR spectroscopy is commonly used to identify and characterize organic and inorganic compounds. It provides information about the functional groups present in a molecule and the bonding between atoms. This helps in the structural elucidation of compounds during organic synthesis, pharmaceutical research,...
1.3K
Measuring Reaction Rates03:09

Measuring Reaction Rates

26.3K
Polarimetry finds application in chemical kinetics to measure the concentration and reaction kinetics of optically active substances during a chemical reaction. Optically active substances have the capability of rotating the plane of polarization of linearly polarized light passing through them—a feature called optical rotation. Optical activity is attributed to the molecular structure of substances. Normal monochromatic light is unpolarized and possesses oscillations of the electrical...
26.3K
Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

3.1K
The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
3.1K
Aldehydes and Ketones with Amines: Imine Formation Mechanism01:23

Aldehydes and Ketones with Amines: Imine Formation Mechanism

6.6K
Imine formation involves the addition of carbonyl compounds to a primary amine. It begins with the generation of carbinolamine through a series of steps involving an initial nucleophilic attack and then several proton transfer reactions. The second part includes the elimination of water, as a leaving group, to give the imine.
Imines are formed under mildly acidic conditions. A pH of 4.5 is ideal for the reaction.
If the pH is low or the solution is too acidic, the reaction slows down in the...
6.6K
Photoluminescence: Applications01:14

Photoluminescence: Applications

518
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
518

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Research Progress of Purely Organic Luminophores in the Field of Electrochemiluminescence.

Critical reviews in analytical chemistry·2026
Same author

Cathodic aggregation-induced electrochemiluminescence sensor based on trinuclear iridium complexes for sensing Cu<sup>2+</sup> ions.

Analytica chimica acta·2026
Same author

Activation-induced cytidine deaminase (AID) suppresses the activity of HBV EnhII/CP by downregulating FANCE expression.

Virus genes·2026
Same author

Dual emitting solid-state electrochemiluminescence of Tetraphenylethylene-embedded mononuclear ruthenium complex matrices for detecting kanamycin.

Food chemistry·2026
Same author

Non-covalent interface engineering of multi-layer graphene cement composites using graphene oxide.

iScience·2026
Same author

Hotspots of N2O accumulation in the soil profile of alternate wetting and drying paddy fields.

Frontiers in plant science·2026

Related Experiment Video

Updated: Oct 7, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
14:11

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

6.3K

Imidazole Compounds: Synthesis, Characterization and Application in Optical Analysis.

Junjie Wang1, Xin Ding1, Zhenni Lan1

  • 1Guangxi Key Laboratory of Electrochemical and Magneto-chemical Functional Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, P.R. China.

Critical Reviews in Analytical Chemistry
|January 10, 2022
PubMed
Summary

This review explores imidazole compounds for optical analysis. Their unique properties enable applications in sensitive and selective fluorescence probes, colorimetric sensors, and other optical sensing technologies.

Keywords:
Imidazolecolorimetryelectrochemiluminescencefluorescenceoptical analysis

More Related Videos

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
10:14

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography

Published on: May 16, 2014

12.7K
Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

14.0K

Related Experiment Videos

Last Updated: Oct 7, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
14:11

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

6.3K
Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
10:14

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography

Published on: May 16, 2014

12.7K
Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

14.0K

Area of Science:

  • Organic Chemistry
  • Analytical Chemistry
  • Materials Science

Background:

  • Imidazole is a π electron-rich aromatic heterocyclic compound with unique optical properties.
  • The nitrogen atoms in imidazole facilitate coordination with metal ions, forming metal-organic frameworks.
  • Imidazole compounds are increasingly recognized for their potential in optical analysis applications.

Purpose of the Study:

  • To review the synthesis, characterization, and applications of imidazole compounds in optical analysis.
  • To highlight research progress in imidazole-based optical sensing technologies.
  • To suggest future directions for developing highly sensitive and selective imidazole-containing sensors.

Main Methods:

  • Literature review focusing on imidazole compound synthesis and characterization.
  • Analysis of diverse optical sensing applications including fluorescence probes, colorimetric probes, and electrochemiluminescence sensors.
  • Examination of advanced techniques like fiber optical sensing and surface plasmon resonance.

Main Results:

  • Imidazole compounds exhibit versatile optical properties suitable for various sensing platforms.
  • Significant advancements have been made in utilizing imidazole derivatives as sensitive and selective optical probes.
  • A range of applications, from fluorescence to SPR sensing, demonstrate the utility of imidazole compounds.

Conclusions:

  • Imidazole compounds offer a promising platform for advanced optical sensing.
  • Further research into imidazole-based materials can lead to next-generation sensors with enhanced performance.
  • The development of novel imidazole-containing sensors holds potential for high-sensitivity and high-selectivity analytical applications.