Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Large scale studies with vitamin C.

T W Anderson

    Acta Vitaminologica Et Enzymologica
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Daily vitamin C supplements may reduce common cold disability but not infection frequency. Individual nutritional status influences vitamin C effectiveness, necessitating large, double-blind trials.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Characterization of a Vascular Wilt of Erythroxylum coca Caused by Fusarium oxysporum f. sp. erythroxyli Forma Specialis Nova.

    Plant disease·2019
    Same author

    Erratum to: Abstracts of the 53rd Annual Meeting of the EASD, Lisbon 2017. Abstract 788: 'Pharmacokinetics and tolerability of oral semaglutide in subjects with renal impairment'.

    Diabetologia·2017
    Same author

    Vitamin therapy: too much or too little?

    Canadian family physician Medecin de famille canadien·2010
    Same author

    Price of progress.

    Canadian Medical Association journal·2010
    Same author

    Sudden death from ischemic heart disease in ontario.

    Canadian Medical Association journal·2010
    Same author

    Metacarpal cortical measurements.

    Canadian Medical Association journal·2010
    Same journal

    [Effects of administration of moderate doses of etretinate (RO 10-9359) on rats deficient in vitamin A].

    Acta vitaminologica et enzymologica·1985
    Same journal

    [High resolution liquid chromatography (HPLC) analysis of the vitamin A and beta-carotene content of heat-treated precooked food].

    Acta vitaminologica et enzymologica·1985
    Same journal

    Multivitamin-mineral supplementation: effects on blood chemistries of college-age women.

    Acta vitaminologica et enzymologica·1985
    Same journal

    "ESVITAF". Survey on the vitamin status of the French: relationships between nutrient intake and biochemical indicators.

    Acta vitaminologica et enzymologica·1985
    Same journal

    Relationships between biotin and DNA contents and DNA turnover in lymphoid organs: thymus, lymph nodes and spleen.

    Acta vitaminologica et enzymologica·1985
    Same journal

    Repletion and depletion of serum alpha and beta carotene in humans with carrots and an algae-derived supplement.

    Acta vitaminologica et enzymologica·1985
    See all related articles

    Area of Science:

    • Nutrition Science
    • Immunology
    • Public Health

    Background:

    • Common colds and winter illnesses cause significant disability.
    • Vitamin C (ascorbic acid) is widely studied for its potential health benefits.
    • Previous trials on vitamin C efficacy have yielded variable results.

    Purpose of the Study:

    • To evaluate the impact of regular and supplemental vitamin C on common cold and winter illness outcomes.
    • To explore factors influencing vitamin C's effectiveness, such as initial nutritional status.
    • To assess vitamin C's effect on infection frequency, well-being, and serum cholesterol.

    Main Methods:

    • Utilized a strictly double-blind trial design due to high individual variability in infection susceptibility.
    • Administered regular daily vitamin C supplements with additional doses during illness.

    Related Experiment Videos

  • Monitored outcomes including disability, infection frequency, sense of well-being, and serum cholesterol levels.

    • Main Results:

    • Vitamin C supplementation reduced the disability associated with common colds and winter illnesses.
    • Little to no effect was observed on the frequency of infections.
    • No significant impact on the sense of well-being or serum cholesterol levels was detected.

    Conclusions:

    • Regular and supplemental vitamin C can mitigate common cold and winter illness disability.
    • Effectiveness may be more pronounced in individuals with lower initial nutritional status.
    • Further research is needed to understand potential sensitivities and withdrawal effects.