Related Experiment Video

Updated: Oct 7, 2025

Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches
06:51

Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches

Published on: September 5, 2025

117

Correlation between Renal Artery Anatomy and Hypertension: A Retrospective Analysis of 3000 Patients

Jiayi Shen1,2, Lingchun Lyu1,2, Xiaoyan Wu1

  • 1Lishui Hospital, Zhejiang University School of Medicine, Lishui, Zhejiang 323000, China.

Evidence-Based Complementary and Alternative Medicine : Ecam
|January 10, 2022
PubMed

Insights

Accessory renal arteries and branches are more common in patients with hypertension. These anatomical variations, along with age and dyslipidemia, are independent risk factors for developing hypertension.

Area of Science:

  • Cardiovascular Imaging
  • Nephrology
  • Radiology

Background:

  • Hypertension is a major global health concern with complex etiologies.
  • Renal artery anatomy variations may play a role in blood pressure regulation.
  • Understanding these variations can inform diagnostic and therapeutic strategies.

Purpose of the Study:

  • To investigate the correlation between renal artery anatomical variations and blood pressure levels.
  • To compare the prevalence of renal artery anomalies in undiagnosed versus diagnosed hypertension groups.

Main Methods:

  • Retrospective analysis of CT imaging and laboratory data from 3000 inpatients and outpatients across 4 Chinese centers.
  • Quantitative vascular analysis was performed to assess morphometric parameters of renal arteries.

Main Results:

  • Accessory renal arteries were found in 23.2% unilaterally and 7.3% bilaterally.
  • The prevalence of accessory renal arteries and renal artery branches was significantly higher in the diagnosed hypertension group.
  • Multivariate analysis identified accessory renal artery (ARA) and age as independent risk factors for hypertension.

Conclusions:

  • Renal artery anatomical variations, particularly accessory renal arteries, are more prevalent in hypertensive individuals.
  • Accessory renal arteries and branches outside the renal hilum are independent risk factors for hypertension.
  • Renin activity, influenced by renal sympathetic nerve activity, is linked to accessory renal arteries.
Abstract

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