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Updated: Oct 7, 2025

Rapid In Situ Hybridization using Oligonucleotide Probes on Paraformaldehyde-prefixed Brain of Rats with Serotonin Syndrome
Published on: September 23, 2015
Serotonin syndrome after an overdose of over-the-counter medicine containing dextromethorphan
Nina Omoto1, Yohei Kanzawa1, Naoto Ishimaru1
1Department of General Internal Medicine Akashi Medical Center Hyogo Japan.
Abstract:
Serotonin syndrome is a potentially life-threatening adverse reaction from therapeutic drug use, intentional self-poisoning, or inadvertent interactions between drugs. We report a case of the serotonin syndrome after an overdose of a commonly available over-the-counter cough medicine, Shin CONTAC sekidome daburu jizokusei. Over-the-counter drugs containing dextromethorphan may, in rare cases, cause health problems requiring hospitalization or worse. An appropriate explanation from the pharmacist at the time of purchase, although not mandatory, is recommended.
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