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Updated: Oct 7, 2025

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Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
Published on: May 4, 2022
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Augmented reality navigation-guided pulmonary nodule localization in a canine model.
Chengqiang Li1, Yuyan Zheng1, Ye Yuan2
1Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Translational Lung Cancer Research
|January 10, 2022
Summary
Augmented reality (AR) navigation offers a safe and effective method for pulmonary nodule localization in a canine model. This innovative technique precisely guided marker implantation, paving the way for future human trials.
Area of Science:
- Medical Technology
- Surgical Navigation
- Pulmonary Medicine
Background:
- Current pulmonary nodule localization methods are limited by specialized equipment and operator skill.
- Augmented reality (AR) navigation presents an innovative solution for intraoperative pulmonary nodule localization.
Purpose of the Study:
- To evaluate the safety and efficacy of an AR navigation-guided pulmonary nodule localization technique.
- To assess the precision and feasibility of AR-guided marker implantation in a canine lung model.
Main Methods:
- Peripheral pulmonary lesions were created in a canine model.
- Preoperative CT scans informed an AR localization plan uploaded to HoloLens.
- Lung localization markers were implanted under AR guidance during general anesthesia.
Main Results:
- 12 lesions in 4 canines were localized with precise marker implantation (median time: 6 minutes).
- Markers were placed with an average distance of 1.9±1.7 mm from lesions.
- No severe pneumothorax occurred, and no marker displacement was observed over 16.5 days.
Conclusions:
- AR navigation-guided pulmonary nodule localization is safe and effective in a canine model.
- Further clinical trials are planned to assess this technology in human patients.

