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The Impact of Trace Elements on Osteoarthritis
Guoyong Li1, Tao Cheng2, Xuefeng Yu1
1Department of Orthopaedics, The Fourth Affiliated Hospital of Nanchang University, Nanchang, China.
Frontiers in Medicine
|January 10, 2022
Summary
Trace elements significantly impact osteoarthritis (OA), a degenerative joint disease. Understanding their roles, like boron and magnesium
Area of Science:
- Orthopedics
- Nutritional Science
- Biochemistry
Background:
- Osteoarthritis (OA) is a degenerative joint disease with complex causes including genetics, biomechanics, and nutrition.
- Trace element status is increasingly recognized as a potential factor in OA development and progression.
Purpose of the Study:
- To review the role of essential and non-essential trace elements in osteoarthritis.
- To explore the mechanisms through which trace elements influence OA pathogenesis.
Main Methods:
- Literature review of studies on trace elements and osteoarthritis.
- Analysis of the biochemical and physiological roles of specific trace elements in joint health.
Main Results:
- Boron and magnesium are essential for bone and joint development.
- Cadmium levels correlate with OA severity.
- Other reviewed trace elements (copper, iron, manganese, selenium, zinc) also play roles in OA.
Conclusions:
- Trace elements are critical modulators of osteoarthritis.
- Further research into trace element supplementation or management may offer therapeutic strategies for OA.
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