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Published on: February 6, 2012
Testicular seminoma arising from infertile testes 6 years after microdissection testicular sperm extraction
Nobuhiko Shimizu1, Taku Naiki1, Daichi Kobayashi1
1Department of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Introduction:
In Western countries, the risk of a testicular germ cell tumor in men with male factor infertility is greater than in the general population. However, Japanese data on this risk are lacking. Additionally, the clinical course for the pathogenesis involved has not been clearly characterized.
Case Presentation:
A 35-year-old Japanese male underwent a right orchiectomy because of a mass in his right scrotum. He had a previous history of microdissection testicular sperm extraction undertaken 6 years ago. The final diagnosis of the right scrotal mass was a stage I seminoma. However, a relapse occurred in the left inguinal lymph node 2 years after surgery and the patient was consequently treated with systemic chemotherapy. Pathological analysis of a microdissection testicular sperm extraction sample yielded a germ cell neoplasia in situ in the right testis.
Conclusion:
In Japan, men who seek an evaluation for infertility might be more likely to develop testicular germ cell tumor.
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