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Spike vs. nucleocapsid serum antigens for COVID-19 diagnosis and severity assessment

Julien Favresse1,2, Jean-Louis Bayart3, Clara David4

  • 1Department of Laboratory Medicine, Clinique St-Luc Bouge, Namur, Belgium.

Clinical Chemistry and Laboratory Medicine
|January 10, 2022
PubMed
Abstract

No abstract available in PubMed .

Keywords:
COVID-19RT-PCRSARS-CoV-2antigenic assaydisease severity

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Coronavirus01:29

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...

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