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On "Biological effects of the superoxide radical" by Irwin Fridovich
1University of Southern California, 3715 McClintock Ave, Los Angeles, CA, 90089-0191, United States; University of California Merced, 5200 North Lake Avenue, Merced, CA 95343, United States.
Archives of Biochemistry and Biophysics
|January 10, 2022
Abstract:
Irwin Fridovich, the discoverer of superoxide dismutase, took the opportunity in this invited paper to address the important question, "Can the superoxide radical exert deleterious effects independent of participating with H2O2 in the production of the hydroxyl radical?" The affirmative answer that he reached was correct although subsequent research on peroxynitrite has provided more complexity.