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Updated: Oct 7, 2025

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Diabetic Mastopathy. Review of Diagnostic Methods and Therapeutic Options
Paweł Guzik1, Tomasz Gęca2, Paweł Topolewski3
1Department of Gynecology and Obstetrics, City Hospital, 35-241 Rzeszow, Poland.
Abstract:
Diabetic mastopathy is a rare breast condition that may occur in insulin-treated men and women of any age. The etiology is still unclear; however, the autoimmunological background of the disease is highly suspected. The changes in diabetic mastopathy may mimic breast cancer; therefore, its diagnostic process is demanding, and treatment options are not clear and limited. Lesions in DM are usually multiple; therefore, surgical removal is not fully effective. A well-done anamnesis with core-needle biopsy is essential and definitive in most cases. In this review, we summarize up-to-date knowledge of diagnostic methods and therapeutic options for diabetic mastopathy treatment and present three cases of diabetic mastopathy-type lesions in ultrasound and radiological examinations.
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