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Related Experiment Video

Updated: Oct 7, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice

Published on: November 27, 2019

Leptin and Metabolic Programming.

Catalina Picó^1,2,3, Mariona Palou^1,2,3

¹Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics, Biomarkers and Risk Evaluation), University of the Balearic Islands, 07122 Palma, Spain.

|January 11, 2022

Summary

Leptin plays a crucial role in metabolic programming throughout life. This special issue explores leptin

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Area of Science:

Endocrinology and Metabolism
Nutritional Science
Developmental Biology

Background:

Leptin is a key hormone regulating energy balance and metabolism.
Its influence extends from early development to adult cardiometabolic health.
This special issue focuses on leptin's multifaceted roles.

Discussion:

Investigates leptin's presence and function in milk and amniotic fluid.
Examines interactions between leptin and other breast milk components.
Explores the impact of environmental factors on leptin's action and metabolic programming.

Key Insights:

Leptin's function is critical for cardiometabolic outcomes across the lifespan.
Novel roles of milk-borne and amniotic leptin are highlighted.
Environmental influences significantly modulate leptin's programming effects.

Outlook:

Further research into leptin's developmental roles is warranted.
Understanding environmental impacts can inform strategies for metabolic health.
Potential therapeutic targets related to leptin signaling may emerge.